The Restylane family of dermal fillers used to treat fine lines and wrinkles, and add volume to the cheeks, lips, and various other areas. Restylane was the first hyaluronic acid filler approved by the U.S. Food and Drug Administration and has since grown into a diverse family of fillers.

The Restylane line of fillers includes a wide variety of products formulated to achieve specific outcomes.

The Restylane family of fillers includes:

  • Restylane Kysse 
  • Restylane Silk
  • Restylane Lyft 
  • Restylane 
  • Restylane-L
  • Restylane Refyne 
  • Restylane Defyne 
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About this product

What to expect

Treatment time varies depending on the number of areas to be treated, but can be as short as 15 minutes. Numbing cream will typically be applied prior to injections in order to make the treatment as comfortable as possible. Restylane filler is injected using a very fine needle or a micro-cannula to achieve your desired outcomes, and your provider may gently massage the area after the initial injection. After your treatment, results are visible immediately. For the first 1-2 weeks, it is normal to experience side effects such as swelling, bruising, redness, or tenderness at the injection site. To ensure that you are a good candidate for hyaluronic acid dermal fillers, your provider will have an in-depth consultation with you prior to treatment.

Targeted Areas

Each of the Restylane fillers is designed to provide natural, lasting results for specific areas of concern. Restylane Kysse and Restylane Silk both target the lips and wrinkles surrounding the mouth known as perioral wrinkles. Restylane Lyft is indicated for moderate to severe wrinkles and volume loss. Some of the most common targeted areas include nasolabial folds, cheeks, and hands. Restylane, Restylane-L , and Restylane Refyne are versatile fillers with varying consistencies and volumes. They are all used to target multiple facial concerns, including moderate to severe wrinkles, facial folds, and (in some cases) lips. Restylane Defyne is used to target facial wrinkles and folds, as well as the chin. Chin augmentation using Restylane Devyne balances the profile for patients with chin retrusion.

How it's work

The Restylane family of fillers is composed of non-animal hyaluronic acid and is developed to mimic the hyaluronic acid that occurs naturally in the human body. Restylane fillers vary in volume and texture in order to take on the natural look and feel of the treated area.


Duration of results may vary based on the treated area and the degree of correction. With full treatment, some results can last as long as 12-18 months, however maintenance appointments within 6-9 months are typically recommended.